Ergothioneine

Ergothioneine is a unique, naturally occurring antioxidant that the human body cannot produce on its own and must obtain through diet. Often recognized as a premium antioxidant, it plays a vital role in:

• Supporting cellular health and integrity.

• Maintaining a healthy inflammatory response.

• Supporting healthy aging and skin vitality.

As a powerful defender against oxidative stress, Ergothioneine helps protect your cells from environmental damage.

The Evolution of Ergothioneine

• 1909: First isolated from ergot by French chemist Charles Tanret.

• 2005: German scientists (Dirk Gründemann team) discover the specific transporter protein, OCTN1, confirming its unique role in human cells.

• 2018: Renowned biochemist Dr. Bruce Ames highlights it as a "longevity nutrient" due to its critical cellular protective functions.

• 2017–2019: Granted GRAS status (Generally Recognized As Safe) for food use by the US FDA and approved in the EU.

• 2024: Officially accepted as a novel food ingredient by China’s National Health Commission.

• 2025: Featured in Cell sub-journals for its significant potential in supporting healthy aging and combating oxidative stress.

• Feb 2025: L-Ergothioneine (Dr.Ergo®) receives renewed US FDA GRAS certification, reinforcing its global safety profile.

How Ergothioneine Works

A rare amino acid derivative that supports skin barrier integrity from within. It delivers targeted antioxidant protection to neutralise free radicals and help maintain skin elasticity.